Biogram

University of Lodz,  10/2017 – 12/2024 

• Doctoral Studies: Chemistry 

Dissertation title: Synthesis and biological studies of organometallic conjugates of kinesin-5 inhibitors 5 


University of Lodz, 10/2015 - 06/2017 

• Master’s Degree: Chemistry in Science and Industry

Dissertation title: Synthesis of metallocene analogs of selected anti-mitotic compounds 


University of Lodz,  10/2013 - 09/2015

 • Bachelor’s Degree: Chemistry in Science and Industry

 Dissertation title: Polymerization activators and inhibitors of tubulin

Osiągnięcia


· Karolina Kowalczyk, Andrzej Błauż, Krzysztof Krawczyk, Błażej Rychlik, Damian Plażuk Design and Synthesis of Ferrocenyl 1,4-Dihydropyridines and Their Evaluation as Kinesin-5 Inhibitors,

 Dalton Trans., 2024, 53, 16038-16053 


· Karolina Kowalczyk, Andrzej Błauż, Daniel Moscoh Ayine -Tora, Christian G. Hartinger, Błażej Rychlik, Damian Plażuk, Design, Synthesis, and Evaluation of Biological Activity of Ferrocene-Ispinesib Hybrids: Impact of a Ferrocenyl Group on the Antiproliferative and Kinesin Spindle Protein Inhibitory Activity, Chem.Eur. J., 2023, 29, e202300813 


· Anna Wieczorek-Błauż, Karolina Kowalczyk, Andrzej Błauż, Anna Makal, Sylwia Pawlędzio, Chatchakorn Eurtivong, Homayon J. Arabshahi, Jóhannes Reynisson, Christian G. Hartinger, Błażej Rychlik, Damian Plażuk, Impact of the ferrocenyl group on cytotoxicity and KSP inhibitory activity of ferrocenyl monastrol conjugates Dalton Trans., 2022, 51, 491-508 


· K. Kowalczyk, A. Błauż, W. Ciszewski, A. Wieczorek, B. Rychlik, D. Plazuk,. – Colchicine metallocenyl bioconjugates showing high antiproliferative activities against cancer cell lines, 

 Dalton Trans., 2017, 48, 17041-17052


 · D. Plażuk, A. Wieczorek, W. M. Ciszewski, K. Kowalczyk, A. Błauż, S. Pawlędzio, A. Makal, C. Eurtivong, H. J. Arabshahi, J. Reynisson, C. G. Hartinger and B. Rychlik, Synthesis and in vitro Biological Evaluation of Ferrocenyl Side-Chain-Functionalized Paclitaxel Derivatives, ChemMedChem, 2017, 12, 1882–1982


Czym się zajmuję - opis stanowiska

chemist, scientific-technical employee

Laboratory of Molecular Spectroscopy

Performing/Recording NMR SpectraTechnical Maintenance of NMR Spectrometers (Avance III and AvanceNeo Spectrometer equipped with a Prodigy cryoprobe), including refilling cryogenic liquids (liquid nitrogen and liquid helium)Administrative Support Related to Conducted AnalysesConducting Scientific Research


Dyżury

chemist, scientific-technical employee

Laboratory of Molecular Spectroscopy

Tamka 12 room: 4-221 91-403 Łódź

Kontakt

chemist, scientific-technical employee

Laboratory of Molecular Spectroscopy

phone: 42-635-57-56

phone: 42-635-57-54

e-mail: psm@chemia.uni.lodz.pl

www:

Tamka 12
91-403 Łódź

Tamka 12 room: 4-221 91-403 Łódź

UNIVERSITY OF LODZ

Narutowicza 68, 90-136 LODZ

fax: 00 48 42/665 57 71, 00 48 42/635 40 43

NIP: 724 000 32 43

Funduszepleu
Projekt Multiportalu UŁ współfinansowany z funduszy Unii Europejskiej w ramach konkursu NCBR